The influence of pro, para and postbiotics derived from lactic acid bacteria on pathogens with biofilm-forming abilities

Abstract

The lactic acid bacteria are widely used and generally considered safe due to their ability to produce various beneficial compounds. In this study, the two bacteria Streptococcus thermophilus and Lactobacillus plantarum 299v were examined. The main goal was to characterize and assess the probiotic potential of these two strains by studying their tolerance to different pH levels, bile salts, temperature, and their ability to form biofilms through autoaggregation. Their antibacterial effect were also investigated. The two strains demonstrated promising results. They were able to survive in a range of temperatures and resist various pH levels and bile salt concentrations. They also exhibited high autoaggregation and coaggregation capacities, indicating strong biofilm formation. In conclusion, this study suggests that the two strains possess probiotic properties. However, further studies are still needed to fully confirm their effectiveness and safety.